veqdera
(:+ ! * * ARCHITECT * * ! +:)
★★
- Joined
- Aug 1, 2021
- Posts
- 2,174
@Nopish
I still risk sending my DNA to the Jews though.
Trueits not a scam its just highly inaccurate
SNP ID | Chr: Basepair Position | Gene | Effective Allele | Amino Acid Substitution | No.of Carriers | Beta±SE | P Value | maxLDL≥190 (%) |
---|---|---|---|---|---|---|---|---|
rs141502002 | 1:55524222 | PCSK9 | T | Arg469Trp | 1147 | 9.4±1.1 | 3.71×10–17 | 17.9 |
rs12713559 | 2:21229068 | APOB | A | Arg3558Cys | 366 | 9.9±2.0 | 6.32×10–7 | 15.3 |
rs5742904 | 2:21229160 | APOB | T | Arg3527Gln | 256 | 43.5±2.4 | 3.40×10–75 | 42.2 |
rs768563000 | 19:11217264 | LDLR | A | Glu240Ter | 34 | 20.3±6.5 | 1.8×10–3 | 26.5 |
rs151207122 | 19:11218157 | LDLR | T | Arg303Trp | 49 | 36.2±5.4 | 2.16×10–11 | 36.7 |
rs121908030 | 19:11218160 | LDLR | A | Asp304Tyr | 30 | 80.2±6.9 | 4.67×10–31 | 66.7 |
rs201573863 | 19:11231154 | LDLR | T | Pro699Leu | 51 | 44.0±5.3 | 1.03×10–16 | 51.0 |
rs137853964 | 19:11240278 | LDLR | A | Val827Ile | 328 | 12.6±2.1 | 1.67×10–9 | 18.0 |
Population | Group | Sample Size | Ref Allele | Alt |
---|
Population | Group | Sample Size | Ref Allele | Alt Allele |
---|---|---|---|---|
Total | Global | 199288 | C=0.999729 | T=0.000271 |
European | Sub | 169946 | C=0.999953 | T=0.000047 |
African | Sub | 4954 | C=0.9923 | T=0.0077 |
African Others | Sub | 176 | C=1.000 | T=0.000 |
African American | Sub | 4778 | C=0.9920 | T=0.0080 |
Asian | Sub | 6350 | C=0.9998 | T=0.0002 |
East Asian | Sub | 4502 | C=0.9998 | T=0.0002 |
Can you teach me how to read thatYou would think so, wouldn't you?
Observe:
"My doctors don't know why my cholesterol is so high!" - Mother
I've had 30X whole genome sequencing. Mother has been genotyped.
Table 2. Individual FH Variants (≥30 carriers) Associated With Elevated maxLDL-C Among 331 107 Multiethnic Veterans
SNP ID Chr: Basepair Position Gene Effective Allele Amino Acid Substitution No.of Carriers Beta±SE P Value maxLDL≥190 (%) rs141502002 1:55524222 PCSK9 T Arg469Trp 1147 9.4±1.1 3.71×10–17 17.9 rs12713559 2:21229068 APOB A Arg3558Cys 366 9.9±2.0 6.32×10–7 15.3 rs5742904 2:21229160 APOB T Arg3527Gln 256 43.5±2.4 3.40×10–75 42.2 rs768563000 19:11217264 LDLR A Glu240Ter 34 20.3±6.5 1.8×10–3 26.5 rs151207122 19:11218157 LDLR T Arg303Trp 49 36.2±5.4 2.16×10–11 36.7 rs121908030 19:11218160 LDLR A Asp304Tyr 30 80.2±6.9 4.67×10–31 66.7 rs201573863 19:11231154 LDLR T Pro699Leu 51 44.0±5.3 1.03×10–16 51.0 rs137853964 19:11240278 LDLR A Val827Ile 328 12.6±2.1 1.67×10–9 18.0
Effects of Genetic Variants Associated with Familial Hypercholesterolemia on Low-Density Lipoprotein-Cholesterol Levels and Cardiovascular Outcomes in the Million Veteran Program
Background: Familial hypercholesterolemia (FH) is characterized by inherited high levels of LDL-C (low-density lipoprotein cholesterol) and premature coronary heart disease. Over a thousand low-frequwww.ahajournals.org
Mother:
View attachment 597297
View attachment 597298
Myself:
View attachment 597299
Population Group Sample Size Ref Allele Alt
Population Group Sample Size Ref Allele Alt Allele Total Global 199288 C=0.999729 T=0.000271 European Sub 169946 C=0.999953 T=0.000047 African Sub 4954 C=0.9923 T=0.0077 African Others Sub 176 C=1.000 T=0.000 African American Sub 4778 C=0.9920 T=0.0080 Asian Sub 6350 C=0.9998 T=0.0002 East Asian Sub 4502 C=0.9998 T=0.0002
rs141502002 RefSNP Report - dbSNP - NCBI
www.ncbi.nlm.nih.gov
Indeed. Mother has the illness while I am carrier for a very rare variant of it. The test was almost certainly accurate.