J
joejutish
Greycel
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- Joined
- Mar 31, 2024
- Posts
- 97
weird ive been searching the entire posts regarding a proper counter to this sentiment here
"Genetic factors can explain more than 70% of the phenotypic facial variation in facial size, nose (width, prominence and height), lips prominence and inter-ocular distance."
"The P561T polymorphism of the growth hormone receptor gene has an inhibitory effect on mandibular growth in young children"
The P561T polymorphism of the growth hormone receptor gene has an inhibitory effect on mandibular growth in young children
Abstract. P561T heterozygous missense mutation in the growth hormone receptor (GHR) is a candidate genetic polymorphism (single-nucleotide polymorphism) foacademic.oup.com
"Linkage analyses have, thus far, shown the statistical significance of such loci as 1p22. 1, 1p22. 3, 1p32. 2, 1p36, 3q26. 2, 4p16. 1, 6q25, 11q22, 12pter-p12. 3, 12q13. 13, 12q23, 12q24. 11, 14q24. 3 to 31.2, and 19p13. 2. The following appear among candidate genes: MATN1, EPB41, growth hormone receptor, COL2A1, COL1A1, MYO1H, DUSP6, ARHGAP21, ADAMTS1, FGF23, FGFR2, TBX5, ALPL, HSPG2, EVC, EVC2, the HoxC gene cluster, insulin-like growth factor 1, PLXNA2, SSX2IP, TGFB3, LTBP2, MMP13/CLG3, KRT7, and FBN3. On the other hand, MYH1, MYH2, MYH3, MYH7, MYH8, FOXO3, NFATC1, PTGS2, KAT6B, HDAC4, and RUNX2 expression is suspected to be involved in the epigenetic regulations behind the mandibular prognathism phenotype."
"Genetic factors significantly contribute to dentofacial and orthodontic variations.
Heritability proportions of over 60% have been reported for features like facial dimensions, dental spacing, and arch dimensions (2)."
"A Swedish study based on 124 skulls from the 500 years preceding the seventeenth century found that the medieval skulls had somewhat smaller teeth and brain cases but larger jaws and wider dental arches than those of a modern population. 4 Other trends that have been reported include a reduction in palatal width between the Romano-British period and the nineteenth century 5, 6 and reductions in bi-zygomatic and maxillary widths between the twelfth and nineteenth centuries. 7"